NAFLD

https://pubmed.ncbi.nlm.nih.gov/34321421/ NAFLD

J Pediatr Gastroenterol Nutr. 2021 Jul 27.
doi: 10.1097/MPG.0000000000003253.Online ahead of print.

Unhealthy Eating, Psychopathology, and Nonalcoholic Fatty Liver Disease in Youth Presenting for Bariatric Surgery

Sanita L Ley 1, Meg H Zeller, Jennifer Reiter-Purtill, David E Kleiner, John Dixon, Stavra Xanthakos, Teen View Study Group and in collaboration with the Teen-LABS Consortium
Affiliations expand
PMID: 34321421

Abstract

Published on: 
Jul-2021

https://www.ncbi.nlm.nih.gov/pubmed/27417217

Lin YC, Chang PF, Lin HF, Liu K, Chang MH, Ni YH. J Hepatol. 2016 Dec;65(6):1209-1216. doi: 10.1016/j.jhep.2016.06.029.

Abstract

BACKGROUND & AIMS:

Autophagy has been shown to be crucial in the regulation of the intracellular lipid stores in hepatocytes. We hypothesize that immunity-related GTPase family M (IRGM) gene (an autophagy-related gene) variants confer the susceptibility to non-alcoholic fatty liver disease (NAFLD) development.

METHODS:

Published on: 
Dec-2016

https://pubmed.ncbi.nlm.nih.gov/35327746/ NAFLD

Children (Basel). 2022 Mar 8;9(3):374.
doi: 10.3390/children9030374.

Variation in Alanine Aminotransferase in Children with Non-Alcoholic Fatty Liver Disease

Eduardo Castillo-Leon 1 2, Heather L Morris 3, Cheryl Schoen 3, Jacob Bilhartz 4, Patrick McKiernan 5, Tamir Miloh 6, Sirish Palle 7, Mohammad Nasser Kabbany 8, Breda Munoz 3, Andrea R Mospan 3, Bryan Rudolph 9, Stavra A Xanthakos 10, Miriam B Vos 11, Target-Nash Investigators

Abstract

Background: Pediatric non-alcoholic fatty liver disease (NAFLD) is a major public health concern. Aminotransferase (ALT) is frequently used for screening and monitoring, but few studies have reported typical patterns of ALT elevation in children.

Published on: 
Mar-2022

https://www.ncbi.nlm.nih.gov/pubmed/31444465 NAFLD
Eur J Clin Nutr. 2019 Aug 23. doi: 10.1038/s41430-019-0493-y. [Epub ahead of print]
Vitamin D deficiency: prevalence and association with liver disease severity in pediatric nonalcoholic fatty liver disease.
Yodoshi T1, Orkin S1, Arce-Clachar AC1,2, Bramlage K1, Liu C3, Fei L2,3, El-Khider F4, Dasarathy S4, Xanthakos SA1,2, Mouzaki M5,6.

Abstract

BACKGROUND/OBJECTIVES:
To determine associations between serum 25-hydroxyvitamin D (25(OH)-D) concentrations and histologic nonalcoholic fatty liver disease (NAFLD) severity.

SUBJECTS/METHODS:

Published on: 
Aug-2019

https://www.ncbi.nlm.nih.gov/pubmed/29084519 NAFLD

BMC Public Health. 2017 Oct 30;17(1):851. doi: 10.1186/s12889-017-4868-5.

Waist-to-height ratio is a useful index for nonalcoholic fatty liver disease in children and adolescents: a secondary data analysis. Lin MS, Lin TH, Guo SE, Tsai MH, Chiang MS, Huang TJ, Chen MY.

Abstract

BACKGROUND:

Nonalcoholic fatty liver disease (NAFLD) is a global problem and pediatric obesity has risen dramatically. Early NAFLD might progress to nonalcoholic steatohepatitis (NASH) or liver cirrhosis and significantly increase liver disease-related mortality. We looked for NAFLD predictors in children and adolescents.

METHODS:

Published on: 
Oct-2017

https://www.ncbi.nlm.nih.gov/pubmed/31655133 NAFLD
J Hepatol. 2019 Oct 23. pii: S0168-8278(19)30613-0. doi: 10.1016/j.jhep.2019.10.011.
β-Klotho gene variation is associated with liver damage in children with NAFLD.
Dongiovanni P1, Crudele A2, Panera N3, Romito I4, Meroni M5, De Stefanis C6, Palma A7, Comparcola D8, Fracanzani AL9, Miele L10, Valenti L11, Nobili V12, Alisi A13.

Abstract

BACKGROUND AND AIM:

Published on: 
Oct-2019

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