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NAFLD
https://www.ncbi.nlm.nih.gov/pubmed/28644356
Mendoza, Michael*; Caltharp, Shelley†,‡; Song, Ming§; Collin, Lindsay*; Konomi, Juna V.*; McClain, Craig J.§; Vos, Miriam B.*,‡
Journal of Pediatric Gastroenterology & Nutrition: July 2017 - Volume 65 - Issue 1 - p 89–92
ABSTRACT
Objective:
Animal models and studies in adults have demonstrated that copper restriction increases severity of liver injury in nonalcoholic fatty liver disease (NAFLD). This has not been studied in children. We aimed to determine if lower tissue copper is associated with increased NAFLD severity in children.
Methods:
http://www.ncbi.nlm.nih.gov/pubmed/24345826
Oʼsullivan TA, Oddy WH, Bremner AP, Sherriff JL, Ayonrinde OT, Olynyk JK,
Beilin LJ, Mori TA, Adams LA. Lower fructose intake may help protect against development of non-alcoholic Fatty liver in adolescents with obesity. J Pediatr Gastroenterol Nutr. 2014 May; 58(5): 624-31.
Abstract
OBJECTIVES:
Although obesity is a major risk factor for non-alcoholic fatty liver (NAFL), not all individuals with obesity develop the condition, suggesting that other factors such as diet may also contribute to NAFL development. We evaluated associations between fructose and total sugar intake and subsequent diagnosis of NAFL in adolescents with obesity and without obesity in a population-based cohort.
METHODS:
https://pubmed.ncbi.nlm.nih.gov/33806784/ NAFLD
Children (Basel. 2021 Mar 23;8(3):247.
doi: 10.3390/children8030247.
MAFLD in Obese Children: A Challenging Definition
Anna Di Sessa 1, Stefano Guarino 1, Giuseppina Rosaria Umano 1, Mattia Arenella 1, Salvatore Alfiero 1, Gaetano Quaranta 1, Emanuele Miraglia Del Giudice 1, Pierluigi Marzuillo 1
Abstract
Background: Recently, the new definition of Metabolic (dysfunction) associated fatty liver disease (MAFLD) has gained remarkable scientific interest. We aimed to evaluate the effectiveness of MAFLD definition in selecting obese children at higher cardiovascular risk.
https://www.ncbi.nlm.nih.gov/pubmed/28493388
Schwimmer JB, Behling C, Angeles JE, Paiz M, Durelle J, Africa J, Newton KP, Brunt EM, Lavine JE, Abrams SH, Masand P, Krishnamurthy R, Wong K, Ehman RL, Yin M, Glaser KJ, Dzyubak B, Wolfson T, Gamst AC, Hooker J, Haufe W, Schlein A, Hamilton G, Middleton MS, Sirlin CB. Hepatology. 2017 May 11. doi: 10.1002/hep.29241
Abstract
http://www.ncbi.nlm.nih.gov/pubmed/25529941
( NAFLD http://www.childrenliverindia.org/diseases/term/34 )
Schwimmer JB, Middleton MS, Behling C, Newton KP, Awai HI, Paiz MN, Lam J, Hooker JC, Hamilton G, Fontanesi J, Sirlin CB. Magnetic resonance imaging and liver histology as biomarkers of hepatic steatosis in children with nonalcoholic fatty liver disease. Hepatology. 2015 Jun;61(6):1887-95.
Abstract
http://www.ncbi.nlm.nih.gov/pubmed/27312946
van Zutphen T, Ciapaite J, Bloks VW, Ackereley C, Gerding A, Jurdzinski A, Allgayer de Moraes R, Zhang L, Wolters JC, Bischoff R, Wanders RJ, Houten SM, Bronte-Tinkew D, Shatseva T, Lewis GF, Groen AK, Reijngoud DJ, Bakker BM, Jonker JW, Kim PK, Bandsma RH. J Hepatol. 2016 Jun 13. pii: S0168-8278(16)30263-X. doi: 10.1016/j.jhep.2016.05.046. [Epub ahead of print]
Abstract
BACKGROUND & AIMS:
https://www.ncbi.nlm.nih.gov/pubmed/27312946
van Zutphen T, Ciapaite J, Bloks VW, Ackereley C, Gerding A, Jurdzinski A, de Moraes RA, Zhang L, Wolters JC, Bischoff R, Wanders RJ, Houten SM, Bronte-Tinkew D, Shatseva T, Lewis GF, Groen AK, Reijngoud DJ, Bakker BM, Jonker JW, Kim PK, Bandsma RH. J Hepatol. 2016 Dec;65(6):1198-1208. doi: 10.1016/j.jhep.2016.05.046
Abstract
BACKGROUND & AIMS:
https://www.ncbi.nlm.nih.gov/pubmed/28333768
Mouzaki M, Ling SC, Schreiber RA, Kamath BM. J Pediatr Gastroenterol Nutr. 2017 Mar 22.
Abstract
BACKGROUND:
The literature on the optimal clinical management of pediatric patients with non-alcoholic fatty liver disease (NAFLD) is limited. The objective of this study was to identify discrepancies in the care provided to patients with NAFLD by hepatologists practicing in academic centers across Canada.
METHODS:
A nationwide survey was distributed electronically to all pediatric hepatologists practicing in university-affiliated hospitals using the infrastructure of the Canadian Pediatric Hepatology Research Group. The responses were anonymous.
RESULTS:
https://pubmed.ncbi.nlm.nih.gov/33862225/ NAFLD
Clin Gastroenterol Hepatol. 2021 Apr 13;S1542-3565(21)00448-1.
doi: 10.1016/j.cgh.2021.04.014. Online ahead of print.
Maternal and perinatal risk factors for pediatric non-alcoholic fatty liver disease: A systematic review
Ilya Querter 1, Nele S Pauwels 2, Ruth De Bruyne 3, Ellen Dupont 4, Xavier Verhelst 1, Lindsey Devisscher 5, Hans Van Vlierberghe 1, Anja Geerts 1, Sander Lefere 6
Abstract
https://pubmed.ncbi.nlm.nih.gov/34008183/NAFLD
Hepatology. 2021 May 18.
doi: 10.1002/hep.31910. Online ahead of print.
Maternal early-pregnancy glucose concentrations and liver fat among school age children
Madelon L Geurtsen 1 2, Rama J Wahab 1 2, Janine F Felix 1 2, Romy Gaillard 1 2, Vincent W V Jaddoe 1 2
Abstract
Background and aims: Gestational diabetes seems to be associated with offspring non-alcoholic fatty liver disease. We hypothesized that maternal glucose concentrations across the full range may have persistent effects on offspring liver fat accumulation.
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