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NAFLD
https://www.ncbi.nlm.nih.gov/pubmed/29651819 NAFLD
J Korean Med Sci. 2018 Apr 16;33(16):e122. doi: 10.3346/jkms.2018.33.e122.Biochemical Predictors of Early Onset Non-Alcoholic Fatty Liver Disease in Young Children with Obesity.
Kim JY1, Cho J1, Yang HR1,2.
Abstract
BACKGROUND:
The prevalence of metabolic syndrome (MS) and non-alcoholic fatty liver disease (NAFLD) and their associated risk factors are not well-established in young children with obesity. The purpose of this study was to evaluate the prevalence of early onset NAFLD and identify its biochemical predictors in obese children aged less than 10 years.
METHODS:
http://www.ncbi.nlm.nih.gov/pubmed/25557690
Sanyal AJ, Friedman SL, McCullough AJ, Dimick-Santos L. Challenges andopportunities in drug and biomarker development for nonalcoholic steatohepatitis: Findings and recommendations from an American Association for the Study of Liver Diseases-U.S. Food and Drug Administration Joint Workshop. Hepatology. 2015; 61(4):1392-405.
Abstract
https://pubmed.ncbi.nlm.nih.gov/33505894/ NAFLD
Pediatr Gastroenterol Hepatol Nutr. 2021 Jan;24(1):54-64.
doi: 10.5223/pghn.2021.24.1.54. Epub 2021 Jan 8.
Changes in Liver Enzymes and Metabolic Profile in Adolescents with Fatty Liver following Exercise Interventions
Hamdollah Iraji 1, Vazgen Minasian 1, Roya Kelishadi 2
Abstract
Purpose: Nonalcoholic fatty liver disease (NAFLD) is the most frequent cause of chronic liver diseases in both adults and children with obesity. The aim of this study was to compare the changes in liver enzymes and metabolic profile in adolescents with fatty liver following selected school-based exercise (SBE) and high-intensity interval training (HIIT) interventions.
https://www.ncbi.nlm.nih.gov/pubmed/28356335
Yan Y, Hou D, Zhao X, Liu J, Cheng H, Wang Y, Mi J. Pediatrics. 2017 Mar 29. pii: e20162738. doi: 10.1542/peds.2016-2738. [
Abstract
OBJECTIVE:
To investigate the association of childhood adiposity and change in adiposity status from childhood to adulthood with nonalcoholic fatty liver disease (NAFLD) and abnormal liver enzyme levels in adulthood.
METHODS:
http://www.ncbi.nlm.nih.gov/pubmed/24989077
Ayonrinde OT, Olynyk JK, Marsh JA, Beilin LJ, Mori TA, Oddy WH, Adams LA. Childhood adiposity trajectories and risk of nonalcoholic fatty liver disease in adolescents. J Gastroenterol Hepatol. 2015 Jan; 30(1):163-71.
Abstract
BACKGROUND AND AIM:
Nonalcoholic fatty liver disease (NAFLD) and its metabolic risk factors are recognized during childhood and adolescence. Identification of adolescents at risk of NAFLD from childhood anthropometry may expose opportunities to influence the hepatic and metabolic destinies of individuals. We sought associations between NAFLD diagnosed during adolescence and earlier life trajectories of anthropometry, in a population-based cohort of predominantly Caucasian adolescents.
METHODS:
https://www.ncbi.nlm.nih.gov/pubmed/31651803 NAFLD
J Pediatr Gastroenterol Nutr. 2019 Oct 23. doi: 10.1097/MPG.0000000000002523. [Epub ahead of print]
Childhood Obesity: A Risk Factor for Non-alcoholic Fatty Liver Disease in Adolescence.
Benítez VC1, Alberti G1, Uauy R1,2, Pereira A2, García C1, de Barbieri F1, Corvalán C2, Santos JL1, Mericq V3, Villarroel L1, Gana JC1.
Abstract
Non-alcoholic fatty liver disease (NAFLD), defined as fat accumulation >5% in hepatocytes, may progress to fibrosis or cirrhosis later in life. NAFLD prevalence in adolescents has increased significantly in direct relation with obesity prevalence. Fatty liver has become the most frequent indication for liver transplantation in adults.
OBJECTIVE:
http://www.ncbi.nlm.nih.gov/pubmed/27235307
Suomela E, Oikonen M, Pitkänen N, Ahola-Olli A, Virtanen J, Parkkola R, Jokinen E, Laitinen T, Hutri-Kähönen N, Kähönen M, Lehtimäki T, Taittonen L, Tossavainen P, Jula A, Loo BM, Mikkilä V, Telama R, Viikari JS, Juonala M, Raitakari OT. J Hepatol. 2016 May 24. pii: S0168-8278(16)30206-9. doi: 10.1016/j.jhep.2016.05.020.
Abstract
BACKGROUND & AIMS:
Fatty liver is a potentially preventable cause of serious liver diseases. This longitudinal study aimed to identify childhood risk factors of fatty liver in adulthood in a population-based group of Finnish adults.
METHODS:
https://pubmed.ncbi.nlm.nih.gov/33233601/ NAFLD
Diagnostics (Basel). 2020 Nov 20;10(11):977.
doi: 10.3390/diagnostics10110977.
Circulating Bile Acids Profiles in Obese Children and Adolescents: A Possible Role of Sex, Puberty and Liver Steatosis
Martina Montagnana 1, Elisa Danese 1, Alice Giontella 2, Sara Bonafini 2, Marco Benati 1, Angela Tagetti 2, Andrea Dalbeni 2, Paolo Cavarzere 3, Rossella Gaudino 3, Mairi Pucci 1, Gian Luca Salvagno 1, Franco Antoniazzi 3, Giuseppe Lippi 1, Claudio Maffeis 3, Cristiano Fava 2
Abstract
https://www.ncbi.nlm.nih.gov/pubmed/31885746 NAFLD
Dis Markers. 2019 Dec 3;2019:9560247. doi: 10.1155/2019/9560247. eCollection 2019.
Circulating Hsp90 Isoform Levels in Overweight and Obese Children and the Relation to Nonalcoholic Fatty Liver Disease: Results from a Cross-Sectional Study.
Bălănescu A1,2, Stan I1,2, Codreanu I1,2, Comănici V1,2, Bălănescu E3, Bălănescu P3,41
Abstract
BACKGROUND:
https://pubmed.ncbi.nlm.nih.gov/33224193/ NAFLD
Review
Gastroenterol Res Pract. 2020 Nov 7;2020:8818191.
doi: 10.1155/2020/8818191.eCollection 2020.
Circulating Irisin Levels in Patients with Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis
Jie Hu 1, Yani Ke 2, Fangping Wu 2, Shan Liu 3, Conghua Ji 3, Xiaohong Zhu 1, Ying Zhang 4
Abstract
Background and aims: Previous studies have revealed the close relation of irisin with the occurrence and development of nonalcoholic fatty liver disease (NAFLD). A systematic review and meta-analysis were conducted to evaluate the association of circulating irisin levels and NAFLD.
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