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Acute Liver Failure
http://www.ncbi.nlm.nih.gov/pubmed/25859823
Alonso EM, James LP, Zhang S, Squires RH; Pediatric Acute Liver Failure Study Group. Acetaminophen Adducts Detected in Serum of Pediatric Patients With Acute Liver Failure. J Pediatr Gastroenterol Nutr. 2015 Jul;61(1):102-7.
Abstract
OBJECTIVES:
Previous studies in patients with acute liver failure identified acetaminophen (APAP) protein adducts in the serum of 12% and 19% of children and adults, respectively, with acute liver failure of indeterminate etiology. This article details the testing of APAP adducts in a subset (n = 393) of patients with varied diagnoses in the Pediatric Acute Liver Failure Study Group (PALFSG).
METHODS:
What is Acute liver failure?
Acute liver failure (ALF) is a disorder in which severe acute impairment of liver function, with or without alteration of consciousness in association with liver cell damage in a child with no recognised underlying chronic liver disease
https://www.ncbi.nlm.nih.gov/pubmed/29474400
PLoS One. 2018 Feb 23;13(2):e0193327. doi: 10.1371/journal.pone.0193327. eCollection2018.
Szymczak M, Kaliciński P, Kowalewski G, Broniszczak D, Markiewicz-Kijewska M, Ismail H, Stefanowicz M, Kowalski A, Teisseyre J, Jankowska I, Patkowski W.
Abstract
OBJECTIVES:
Living donor liver transplantation (LDLT) in patients with acute liver failure (ALF) has become an acceptable alternative to transplantation from deceased donors (DDLT). The aim of this study was to analyze outcomes of LDLT in pediatric patients with ALF based on our center's experience.
MATERIAL AND METHODS:
https://www.ncbi.nlm.nih.gov/pubmed/31778017 Acute liver failure
Liver Transpl. 2019 Nov 28. doi: 10.1002/lt.25693. [Epub ahead of print]
Acute liver failure in children: is it time to revise the diagnostic criteria?
Di Giorgio A1, D'Antiga L1.
Author information
Abstract
http://www.ncbi.nlm.nih.gov/pubmed/25557177
Alam S, Lal BB, Khanna R, Sood V, Rawat D. Acute Liver Failure in Infants and Young Children in a Specialized Pediatric Liver Centre in India. Indian J Pediatr. 2015 Oct; 82(10):879-83.
Abstract
OBJECTIVE:
To study the etiological spectrum of acute liver failure in infants and young children and to identify clinical and biochemical markers for metabolic liver disease (MLD).
METHODS:
https://pubmed.ncbi.nlm.nih.gov/34286318/ Acute liver failure
Review
Turk Arch Pediatr. 2021 Feb 3;56(2):108-114.
doi: 10.5152/TurkArchPediatr.2021.190205. eCollection 2021 Mar.
Acute liver failure in newborns
Nilgün Karadağ 1, Aslı Okbay Güneş 1, Güner Karatekin 1
Abstract
http://www.ncbi.nlm.nih.gov/pubmed/23929808
Karkhanis J, Verna EC, Chang MS, Stravitz RT, Schilsky M, Lee WM, Brown RS Jr; Acute Liver Failure Study Group. Steroid use in acute liver failure. Hepatology. 2014 Feb; 59 (2):612-21.
Abstract
https://pubmed.ncbi.nlm.nih.gov/33633086/ Acute Liver Failure
J Pediatr Gastroenterol Nutr. 2021 Feb 24.
doi: 10.1097/MPG.0000000000003103.Online ahead of print.
Applying an Age-Specific Definition to Better Characterize Etiologies and Outcomes in Neonatal Acute Liver Failure
Kristin Borovsky 1, Anna M Banc-Husu, Samantha A Saul, Katie Neighbors, Susan Kelly, Estella M Alonso, Sarah A Taylor
Abstract
Objective: Neonatal acute liver failure (ALF) is a rare disease with high mortality for which no standard age-specific definition exists. To advance the understanding of neonatal ALF we characterize the etiology, presenting features, treatment, and outcomes in infants within 1 month of life.
Presenter: Dr. Chirag Shah Moderator: Dr. Vivek Saraswat
Presenter: Dr. Khushnuma Mullanfiroze Moderators: Dr. Anshu Srivastava, Dr. Archana Kher
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