Progressive Familial Intrahepatic Cholestasis
What is PFIC ?
PFIC as the name stands for is a rare progressive disorder affecting liver due to defect in secretion of bile. As an inherited inability to secrete bile , it accumulates in the liver causing damage and ultimately end stage liver failure.
PFIC is Autosomal recessive disorder and can affect both males and females equally. It is a rare disease affecting about 1 per 1,00,000 births around the world.