Indian J Pathol Microbiol. 2012 Oct;55(4):506-8. doi: 10.4103/0377-4929.107792.

Mycophenolate mofetil-induced colitis with graft versus host disease-like features in a liver transplant recipient.

Patra S, Vij M, Sukanya B, Kapoor D.

Source: Department of Pathology, Global Hospitals and Health City, Chennai, Tamilnadu, India.

Abstract: Mycophenolate mofetil (MMF) is a commonly used immunosuppressive drug in the management of transplant recipients. Gastrointestinal (GI) toxicity (diarrhea) is the most frequently reported adverse event in MMF-treated transplant patients. MMF-induced Graft versus Host Disease has rarely been reported in literature. We report a case of MMF-induced colitis with Graft versus Host Disease-like features, to highlight the importance of high clinical suspicion for its diagnosis, and that appropriate management in such a setting can reduce morbidity and mortality. We also review the relevant literature.

PMID: 23455789 [PubMed - in process]